Tebuconazol 戊唑醇

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戊唑醇

通用名：戊唑醇(Tebuconazole)
化学名：(RS)-1-(4-氯苯基)-4,4-二甲基-3-(1H-1,2,4三唑-1-基甲基)戊-3-醇
分子量：307.8
分子式：C16H22ClN3O
结构式：如图
CAS号：107534-96-3

理化性质：本品为无色晶体，熔点为102.4°C，蒸气压0.0133mPa(20°C)：溶解度(20°C)：水32mg/L，甲苯50-100g/L。
用途：本品属三唑类杀菌剂，是甾醇脱甲基抑制剂，是用于重要经济作物的种子处理或叶面喷洒的高效杀菌剂，可有效地防治禾谷类作物的多种锈病、白粉病、网斑病、根腐病、赤霉病，黑穗病及种传轮斑病等。
规格：95% 、98%原药。125g/L水乳剂，25%乳油，25%可湿性粉剂，43%悬浮剂，80%水分散粒剂，用于叶面喷雾；Raxil,FS(25g/L).DS(20g/kg),WS,LS,用于种子处理。
毒性：按我国农药毒性分级标准，该药属低毒杀菌剂。大鼠急性经口LD50 4000mg/kg，雄小鼠急性经口LD50约2000mg/kg，雌小鼠急性经口LD50 3933mg/kg，大鼠急性经皮LD50>5000mg/kg。大鼠急性吸入LC50(4h)>0.8mg/l空气(气雾剂)、>5.1mg/l(粉剂)。该药对鱼中等毒性，金鱼LC50（96小时）8.7毫克/升。
环境影响：按要求使用对蜜蜂安全。鱼LD50(96h，mg/L)：金雅罗鱼8．7，虹鳟鱼6.4;急性经口LD50(mg/kg)：鸡4438，日本鹑4438(雄)、2912(雌)，北美鹑1988。实验室试验在土中分解很慢,在田间降解较快。
包装：25公斤纸板桶

作用特点
戊唑醇是一种高效、广谱、内吸性三唑类杀菌剂，具有保护、治疗、铲除三大功能，杀菌谱广、持效期长。本品用于防治油菜菌核病，不仅防效好，而且具有抗倒伏，增产作用明显等特点。
对病菌的作用机制为抑制其细胞膜上麦角甾醇的去甲基化，使得病菌无法形成细胞膜，从而杀死病菌。

防治对象与使用方法
小麦散黑穗病：小麦播种前每100千克种子用2%立克秀干拌剂或湿拌剂商品量100～150克(有效成分2～3克)，或用6%立克秀悬浮剂商品量30～45毫升(有效成分1.8～2.7克)拌种。戊唑醇拌种对小麦出芽有抑制作用，一般比正常不拌种晚发芽2~~3天，最多3~~5天，对后期产量没有影响。充分拌均后播种。
玉米丝黑穗病：玉米播种前每100千克种子用2%立克秀干拌剂或湿拌剂商品量400～600克(有效成分8～12克)拌种。充分拌匀后播种。
高粱丝黑穗病：高粱播种前每100千克种子用2%立克秀干拌剂或湿拌剂商品量400～600克(有效成分8～12克)，或用6%立克秀悬浮剂商品量100～150克(有效成分6～9克)拌种，充分拌均后播种。

注意事项
1 接触本剂应遵守农药安全使用操作规程，穿好防护衣服。工作时禁止吸烟和进食。工作结束后，应用肥皂和清水洗脸、手和裸露部位。
2 用本剂处理过的种子，严禁用于人食或动物饲料。
3 本剂应贮存于干燥、通风、阴凉和儿童触及不到的地方。
4 如有中毒情况发生，应立即就医。该药无特殊解毒剂，应对症治疗。
5茎叶喷雾时，在蔬菜幼苗期、果树幼果期应注意使用浓度，以免造成药害

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Tebuconazole
Fungicide

NOMENCLATURE
Common Name: Tebuconazole
IUPAC name (RS)-1-p-chlorophenyl-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol
CAS RN: 107534-96-3

PHYSICAL CHEMISTRY OF ACTIVE INGREDIENT
Form: Colourless crystals; (tech., colourless to light brown powder).
M.p. :105 ºC
V.p.: 1.7 x10-3 mPa (20 ºC) (OECD 104)
KOW: logP = 3.7 (20 °C)
S.g./density: 1.25 (26 °C)
Solubility: In water 36 mg/l (pH 5-9, 20 ºC). In dichloromethane >200, isopropanol, toluene 50-100, hexane <0.1 (all in g/l, 20 ºC).
Stability: Stable to elevated temperatures, and to photolysis and hydrolysis in pure water, under sterile conditions; hydrolysis DT50 >1 y (pH 4-9, 22 °C). See also Environmental Fate.

SPECIFICATION
95%Tech, 25%EC

APPLICATION:
Biochemistry: Steroid demethylation (ergosterol biosynthesis) inhibitor.
Mode of action: Systemic fungicide with protective, curative, and eradicant action. Rapidly absorbed into the vegetative parts of the plant, with translocation principally acropetally.
Uses: As a seed dressing, tebuconazole is effective against various smut and bunt diseases of cereals such as Tilletia spp., Ustilago spp., and Urocystis spp., also against Septoria nodorum (seed-borne), at 1-3 g/dt seed; and Sphacelotheca reiliana in maize, at 7.5 g/dt seed. As a spray, tebuconazole controls numerous pathogens in various crops including: rust species (Puccinia spp.) at 125-250 g/ha, powdery mildew (Erysiphe graminis) at 200-250 g/ha, scald (Rhynchosporium secalis) at 200-312 g/ha, Septoria spp. at 200-250 g/ha, Pyrenophora spp. at 200-312 g/ha, Cochliobolus sativus at 150-200 g/ha, and head scab (Fusarium spp.) at 188-250 g/ha, in cereals; leaf spots (Mycosphaerella spp.) at 125-250 g/ha, leaf rust (Puccinia arachidis) at 125 g/ha, and Sclerotium rolfsii at 200-250 g/ha, in peanuts; black leaf streak (Mycosphaerella fijiensis) at 100 g/ha, in bananas; stem rot (Sclerotinia sclerotiorum) at 250-375 g/ha, Alternaria spp. at 150-250 g/ha, stem canker (Leptosphaeria maculans) at 250 g/ha, and Pyrenopeziza brassicae at 125-250 g/ha, in oilseed rape; blister blight (Exobasidium vexans) at 25 g/ha, in tea; Phakopsora pachyrhizi at 100-150 g/ha, in soya beans; Monilinia spp. at 12.5-18.8 g/100 l, powdery mildew (Podosphaera leucotricha) at 10.0-12.5 g/100 l, Sphaerotheca pannosa at 12.5-18.8 g/100 l, scab (Venturia spp.) at 7.5-10.0 g/100 l, white rot in apples (Botryosphaeria dothidea) at 25 g/100 l, in pome and stone fruit; powdery mildew (Uncinula necator) at 100 g/ha, in grapevines; rust (Hemileia vastatrix) at 125-250 g/ha, berry spot disease (Cercospora coffeicola) at 188-250 g/ha, and American leaf disease (Mycena citricolor) at 125-188 g/ha, in coffee; white rot (Sclerotium cepivorum) at 250-375 g/ha, and purple blotch (Alternaria porri) at 125-250 g/ha, in bulb vegetables; leaf spot (Phaeoisariopsis griseola) at 250 g/ha, in beans; early blight (Alternaria solani) at 150-200 g/ha, in tomatoes and potatoes.
Phytotoxicity: Good plant compatibility in most crops with any formulation, and achieved in more sensitive crops by appropriate formulations, e.g. WP, WG or SC.