Haloxyfop-P-methyl 高效氟吡甲禾灵

高效氟吡甲禾灵

高效氟吡甲禾灵是一种选择性除草剂，用于各种阔叶作物田中防除各种禾 高效氟吡甲禾灵的化学结构式
本科杂草。尤其对芦苇、白茅、狗牙根等多年生顽固禾本科杂草具有卓越的防除效果。对阔叶作物高度安全。低温条件下效果稳定。
其它名称：高效盖草能。
英文名称：haloxyfop-R-methyl。

常用剂型
10.8%高效氟吡甲禾灵乳油。

适用作物
各种阔叶作物。如：棉花、大豆、花生、马铃薯、油菜、油葵、西瓜、麻类、蔬菜等。

防除对象
一年生及多年生禾本科杂草。如：马唐、稗草、千金子、看麦娘、狗尾草、牛筋草、早熟禾、野燕麦、芦苇、白茅、狗牙根等。尤其对芦苇、白茅、狗牙根等多年生顽固禾本科杂草具有卓越的防除效果。

作用机理
高效氟吡甲禾灵施药后能很快被禾本科杂草的叶片吸收，并传导至整个植株，抑制植物分生组织生长，从而杀死杂草。施药期长，对出苗后到分蘖、抽穗初期的一年生和多年生禾本科杂草均具有很好的防除效果。正常使用情况下对各种阔叶作物高度安全。低温、干旱条件下仍能表现出优异的除草效果。

使用方法
（1）防除一年生禾本科杂草，于杂草3-5叶期施药，亩用10.8%高效氟吡甲禾灵乳油20-30毫升，兑水20-25千克，均匀喷雾杂草茎叶。天气干旱或杂草较大时，须适当加大用药量至30-40毫升，同时兑水量也相应加大至25-30千克。
（2）用于防治芦苇、白茅、狗牙根等多年生禾本科杂草时，亩用量为10.8%高效氟吡甲禾灵乳油60-80毫升，兑水25-30千克。在第一次用药后1个月再施药1次，才能达到理想的防治效果。

注意事项
（1）本品使用时加入有机硅助剂可以显著提高药效。
（2）禾本科作物对本品敏感，施药时应避免药液漂移到玉米、小麦、水稻等禾本科作物上，以防产生药害。

haloxyfop-P
Herbicide
HRAC A WSSA 1; aryloxyphenoxypropionate

NOMENCLATURE
haloxyfop-P
IUPAC name (R)-2-[4-(3-chloro-5-trifluoromethyl-2-pyridyloxy)phenoxy]propionic acid
Chemical Abstracts name (R)-(+)-2-[4-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy]phenoxy]propanoic acid
CAS RN [95977-29-0]

haloxyfop-P-methyl
IUPAC name methyl (R)-2-[4-(3-chloro-5-trifluoromethyl-2-pyridyloxy)phenoxy]propionate
Chemical Abstracts name methyl (R)-(+)-2-[4-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy]phenoxy]propanoate
Other names haloxyfop-R CAS RN [72619-32-0] EEC no. 406-250-0 Development codes DE-535 (Dow)

PHYSICAL CHEMISTRY
haloxyfop-P
Mol. wt. 361.7 M.f. C15H11ClF3NO4 Form Colourless crystals. M.p. 70.5-74.5 °C V.p. 3.5 ´ 10-3 mPa (25 °C) KOW logP = 0.27 (pH 7) Solubility In water 375 mg/l (20 ºC). In acetone, dichloromethane, methanol, xylene >639 g/l (20 ºC). pKa 4.27

haloxyfop-P-methyl
Composition The (R)- isomer of haloxyfop-methyl. Mol. wt. 375.7 M.f. C16H13ClF3NO4 Form Clear brown, odourless liquid. B.p. >280 ºC V.p. 0.328 mPa (25 ºC) KOW logP = 4.00 Henry 1.1 ´ 10-3 Pa m3 mol-1 (20 °C, calc.) S.g./density 1.372 (20 °C) Solubility In water 9.08 mg/l (25 ºC). In acetone, cyclohexanone, dichloromethane, ethanol, methanol, toluene, xylene >1 kg/l (20 ºC). Stability DT50 in water 100 d (pH5), 48 d (pH7), 52 h (pH9) (all 25°C). F.p. 186 °C

COMMERCIALISATION
History The methyl ester reported by Bayer S.A. (M. C. Botte et al., Proc. 15th Columa Conf., 1992, 1, 397) and introduced by DowElanco (now Dow AgroSciences). Manufacturers Dow AgroSciences

APPLICATIONS
Biochemistry Fatty acid synthesis inhibitor, by inhibition of acetyl CoA carboxylase (ACCase). Mode of action Haloxyfop-P-methyl is a selective herbicide, absorbed by the foliage and roots, and hydrolysed to haloxyfop-P, which is translocated to meristematic tissues, and inhibits their growth. Uses Haloxyfop-P-methyl is used post-emergence for control of annual and perennial grasses in sugar beet, fodder beet, oilseed rape, potatoes, leaf vegetables, onions, flax, sunflowers, soya beans, vines, strawberries, and other crops. Applied at 52-104 g a.e./ha. Formulation types EC.

haloxyfop-P-methyl
Selected products: 'Gallant Super' (Dow AgroSciences)

OTHER PRODUCTS
haloxyfop-P-methyl
'Eloge' (Dow AgroSciences, Bayer CropScience); 'Galant' (Dow AgroSciences); 'Zellek Super' (Dow AgroSciences)

ANALYSIS
Product analysis by hplc. Residues determined by glc. Details available from Dow AgroSciences.

MAMMALIAN TOXICOLOGY

haloxyfop-P-methyl
Oral Acute oral LD50 for male rats 300, female rats 623 mg/kg. Skin and eye Acute percutaneous LD50 for rats >2000 mg/kg. Non-irritant to skin; slightly irritating to eyes (rabbits). NOEL (2 y) for rats 0.065 mg/kg b.w. daily; no increase in hepatotoxicity. ADI As haloxyfop. EC classification Xn; R22| N; R50, R53

ECOTOXICOLOGY
haloxyfop-P
Birds Acute oral LD50 for bobwhite quail 414 mg/kg. Fish LC50 (96 h) for rainbow trout >50 mg/l. Daphnia LC50 (48 h) >100 mg/l. Algae EC50 (96 h) >70 mg/l. Bees LD50 (48 h, oral and contact) >100 mg/bee.

haloxyfop-P-methyl
Birds Acute oral LD50 for bobwhite quail 1159 mg/kg. Fish LC50 (96 h) for rainbow trout 0.7 mg/l. Daphnia LC50 (48 h) 6.12 mg/l. Algae EC50 (5 d) 1.72 mg/l. Bees LD50 (48 h, oral and contact) >100 mg/bee. Worms LC50 (14 d) 1343 mg/kg.

ENVIRONMENTAL FATE
haloxyfop-P-methyl
Animals In mammals, rapidly converted to the parent acid and eliminated. Plants Hydrolysed to haloxyfop, terminal residue haloxyfop, or conjugates. Soil/Environment DT50 <24 h, forming the parent acid, which is then microbially degraded. Haloxyfop acid degradation approximates to first order kinetics and involves degradation to the pyridinol and other minor metabolites. DT50 9 to 20.5 d, average 14 d (various soil types).